Specification of Glibenclamide [BP/EP/IP/USP]

Synonyms of Glibenclamide: 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)-sulfonyl)-3-cyclohexylurea; Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]-amino]sulfonyl]phenyl]-ethyl]-2-methoxy-; Diabeta; Daonil; Euglucon; Glyburide; Glimel; Glyburide; Micronase; Semi-Daonil; yburide;
Formula of Glibenclamide : C23H28ClN3O5S
CAS RN of Glibenclamide : 10238-21-8
ACX No. of Glibenclamide : X1004244-9
Uses of Glibenclamide : Antidiabetic, Hypoglycemic Agent.
Specification of Glibenclamide: As per IP/BP/EP/USP
Impurity Profile of Glibenclamide :

By HPLC OR TLC

Impurity A :
5-chloro-2-methoxy-N-[2-(4-sulphamoylphenyl)ethyl]benzamide,		 0.5%
Impurity B :
methoxybenzoyl)amino]ethyl]phenyl]sulphonyl]carbamate.		 0.5%
Unknown Impurity 1 0.2%
Unknown Impurity 2 0.1 %
Unknown Impurity 3 0.1%
Total of other impurities 0.5